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Can I run it?

Can a RTX PRO 4500 Blackwell run Red Dead Redemption 2?

Yes, smoothly: about 165 FPS at 1080p Medium with a Ryzen 5 7600.

~165
Every resolution and preset, with a Ryzen 5 7600 and 16 GB RAM.
ResolutionLowMediumHighUltra
1080p~200~165~140~120
1440p~150~120~100~90
4K~90~75~60~55
With other processors (Medium preset).
Processor1080p1440p4K
Ryzen 7 9800X3D~170~125~75
Ryzen 5 7600~165~120~75
Core i5-12400~160~120~75

Questions about this game

Can a RTX PRO 4500 Blackwell run Red Dead Redemption 2?
Yes, smoothly: about 165 FPS at 1080p Medium with a Ryzen 5 7600.
Is the RTX PRO 4500 Blackwell the bottleneck?
The graphics card sets the pace.

How we estimate: a PC exactly at the recommended spec is taken as ~60 FPS at 1080p Medium and one at the minimum spec as ~30 FPS at 1080p Low; your CPU and GPU scores are compared with those, then fixed multipliers for resolution and preset apply. Real results vary with drivers, patches and upscalers.

Game data: IGDB.com · official requirements and artwork from the publishers' Steam pages.